beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptide
BACE2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all BACE2 products
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PAGAANFLAM VDNLQGDSGR GYYLEMLIGT PPQKLQILVD TGSSNFAVAG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- BACE2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
- Synonyms
- AEPLC Peptide, ALP56 Peptide, ASP1 Peptide, ASP21 Peptide, BAE2 Peptide, CEAP1 Peptide, DRAP Peptide, 1110059C24Rik Peptide, AI850424 Peptide, ARP1 Peptide, CDA13 Peptide, beta-site APP-cleaving enzyme 2 Peptide, BACE2 Peptide, Bace2 Peptide
- Background
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This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
Alias Symbols: ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1
Protein Size: 468 - Gene ID
- 25825
- NCBI Accession
- NM_012105, NP_036237
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