Amiloride-Sensitive Cation Channel 3 (ACCN3) (N-Term) Peptide
Quick Overview for Amiloride-Sensitive Cation Channel 3 (ACCN3) (N-Term) Peptide (ABIN8094502)
Target
Source
Application
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Protein Region
- N-Term
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Purpose
- ACCN3 Peptide - N-terminal region
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Amiloride-Sensitive Cation Channel 3 (ACCN3) peptide
ACCN3 Host: Synthetic BP, WB, IHC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ACCN3 antibody ( ARP35152_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
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Background
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Background Information: ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
Alternative Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
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Molecular Weight
- 58kDa
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Gene ID
- 9311
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NCBI Accession
- NP_004760
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UniProt
- Q9UHC3
Target
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