Amiloride-Sensitive Cation Channel 3 (ACCN3) (N-Term) Peptide
Quick Overview for Amiloride-Sensitive Cation Channel 3 (ACCN3) (N-Term) Peptide (ABIN8094503)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- ASIC3 Peptide - N-terminal region
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Sequence
- MKPTSGPEEA RRPASDIRVF ASNCSMHGLG HVFGPGSLSL RRGMWAAAVV
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Amiloride-Sensitive Cation Channel 3 (ACCN3) peptide
ACCN3 Host: Synthetic BP, WB, IHC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- ACCN3 Antibody (ARP83590_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
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Background
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Background Information: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.
Alternative Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
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Molecular Weight
- 58 kDa
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Gene ID
- 9311
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NCBI Accession
- NP_004760
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UniProt
- Q9UHC3
Target
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