Angiopoietin 1 (ANGPT1) (N-Term) Peptide
Quick Overview for Angiopoietin 1 (ANGPT1) (N-Term) Peptide (ABIN8094596)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- ANGPT1 Peptide - N-terminal region
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Sequence
- FAFLAAILTH IGCSNQRRSP ENSGRRYNRI QHGQCAYTFI LPEHDGNCRE
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Angiopoietin 1 (ANGPT1) (AA 20-498) peptide
ANGPT1 Reactivity: Human Host: Escherichia coli (E. coli) SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ANGPT1 Antibody (ARP63106_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Angiopoietin 1 (ANGPT1)
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Background
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Background Information: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alternative Symbols: AGP1, AGPT, ANG1
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Molecular Weight
- 55kDa
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Gene ID
- 284
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NCBI Accession
- NP_001137
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UniProt
- Q15389
Target
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