Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) Peptide
Quick Overview for Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) Peptide (ABIN8096325)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- CASP10 Peptide - C-terminal region
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Sequence
- QSLCNHLKKL VPRHEDILSI LTAVNDDVSR RVDKQGTKKQ MPQPAFTLRK
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-CASP10 Antibody (ARP58999_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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Background
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Background Information: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer.
Alternative Symbols: ALPS2, FLICE2, MCH4
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Molecular Weight
- 57kDa
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Gene ID
- 843
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NCBI Accession
- NP_116759
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UniProt
- Q92851
Target
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