CD207 Molecule, Langerin (CD207) (C-Term) Peptide
Quick Overview for CD207 Molecule, Langerin (CD207) (C-Term) Peptide (ABIN8096502)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- CD207 Peptide - C-terminal region
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Sequence
- GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-CD207 Antibody (ARP63502_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CD207 (CD207 Molecule, Langerin (CD207))
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Background
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Background Information: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Alternative Symbols: CLEC4K
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Molecular Weight
- 36kDa
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Gene ID
- 50489
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NCBI Accession
- NP_056532
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UniProt
- Q9UJ71
Target
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