CD207 Molecule, Langerin (CD207) (C-Term) Peptide
CD207
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974653
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for CD207 Molecule, Langerin (CD207) (C-Term) Peptide (ABIN974653)
Target
CD207
(CD207 Molecule, Langerin (CD207))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD207 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD207 (CD207 Molecule, Langerin (CD207))
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Background
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The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Alias Symbols: CLEC4K
Protein Size: 328 -
Molecular Weight
- 36 kDa
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Gene ID
- 50489
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NCBI Accession
- NM_015717, NP_056532
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UniProt
- Q9UJ71
Target
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