Chloride Channel Kb (CLCNKB) Peptide
Quick Overview for Chloride Channel Kb (CLCNKB) Peptide (ABIN8096918)
Target
Source
Application
-
-
Purpose
- CLCNKB Peptide
-
-
Chloride Channel Kb (CLCNKB) peptide
CLCNKB Host: Synthetic BP, WB, IHC
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-CLCNKB antibody ( ARP34917_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- CLCNKB (Chloride Channel Kb (CLCNKB))
-
Background
-
Background Information: Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94 % sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Alternative Symbols: CLCKB, ClC-K2, ClC-Kb, hClC-Kb
-
Molecular Weight
- 76kDa
-
Gene ID
- 1188
-
NCBI Accession
- NP_000076
-
UniProt
- P51801
Target
-
