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Chloride Channel Kb (CLCNKB) (C-Term) Peptide

CLCNKB Reactivity: Human Host: Synthetic BP
Catalog No. ABIN8096919
$145.08
Plus shipping costs $50.00
100 μg
Shipping to: United States
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Quick Overview for Chloride Channel Kb (CLCNKB) (C-Term) Peptide (ABIN8096919)

Target

CLCNKB (Chloride Channel Kb (CLCNKB))

Origin

Human

Source

  • 8
Synthetic

Application

Blocking Peptide (BP)
  • Protein Region

    C-Term

    Purpose

    CLCNKB Peptide - C-terminal region

    Sequence

    VESTESQILV GIVRRAQLVQ ALKAEPPSWA PGHQQCLQDI LAAGCPTEPV
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    This is a synthetic peptide designed for use in combination with anti-CLCKB Antibody (ARP76018_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Buffer

    Lyophilized powder

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
  • Target

    CLCNKB (Chloride Channel Kb (CLCNKB))

    Background

    Background Information: The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alternative Symbols: CLCKB, ClC-K2, ClC-Kb

    Molecular Weight

    75kDa

    Gene ID

    1188

    UniProt

    P51801
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