Cytohesin 4 (CYTH4) (Middle Region) Peptide
Quick Overview for Cytohesin 4 (CYTH4) (Middle Region) Peptide (ABIN8098458)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- CYTH4 Peptide - middle region
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Sequence
- FVSMNRGINN GSDLPEDQLR NLFDSIKSEP FSIPEDDGND LTHTFFNPDR
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Cytohesin 4 (CYTH4)
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Background
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Background Information: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The structures of this gene and CYTH1 are very similar.
Alternative Symbols: CYT4, PSCD4, DJ63G5.1
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Molecular Weight
- 46 kDa
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Gene ID
- 27128
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NCBI Accession
- NP_037517
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UniProt
- Q9UIA0
Target
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