FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) Peptide
Quick Overview for FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) Peptide (ABIN8101053)
Target
Source
Application
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Purpose
- FXYD5 Peptide
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FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) peptide
FXYD5 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-FXYD5 antibody ( ARP37690_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
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Background
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Background Information: FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.
Alternative Symbols: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241
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Molecular Weight
- 20kDa
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Gene ID
- 53827
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NCBI Accession
- NP_659003
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UniProt
- Q96DB9
Target
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