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FXYD Domain Containing Ion Transport Regulator 5 (FXYD5) Peptide

FXYD5 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN977160
  • Target See all FXYD5 products
    FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
    Origin
    Human
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-FXYD5 antibody (Catalog #: ARP37690_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
    Synonyms
    FXYD5 Peptide, DYSAD Peptide, IWU1 Peptide, KCT1 Peptide, OIT2 Peptide, PRO6241 Peptide, RIC Peptide, EF-8 Peptide, Oit2 Peptide, FXYD domain containing ion transport regulator 5 Peptide, FXYD domain-containing ion transport regulator 5 Peptide, FXYD5 Peptide, Fxyd5 Peptide
    Background
    FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.

    Alias Symbols: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241

    Protein Size: 178
    Molecular Weight
    20 kDa
    Gene ID
    53827
    NCBI Accession
    NM_144779, NP_659003
    UniProt
    Q96DB9
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