Glucosidase, Beta, Acid (GBA) (C-Term) Peptide
Quick Overview for Glucosidase, Beta, Acid (GBA) (C-Term) Peptide (ABIN8101563)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- GBA Peptide - C-terminal region
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Sequence
- EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-GBA Antibody (ARP61322_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GBA (Glucosidase, Beta, Acid (GBA))
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Background
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Background Information: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Alternative Symbols: GBA1, GCB, GLUC
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Molecular Weight
- 59kDa
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Gene ID
- 2629
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NCBI Accession
- NP_000148
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UniProt
- P04062
Target
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