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Glucosidase, Beta, Acid (GBA) Peptide

GBA Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN936300
  • Target See all GBA products
    GBA (Glucosidase, Beta, Acid (GBA))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of GBA antibody,
    Alternative Names: GBA control peptide, GBA antibody Blocking Peptide, Anti-GBA Blocking Peptide, glucosidase, beta, acid Blocking Peptide, GBA1 Blocking Peptide, GCB Blocking Peptide, GLUC Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    GBA (Glucosidase, Beta, Acid (GBA))
    Synonyms
    GBA1 Peptide, GCB Peptide, GLUC Peptide, BETA-GLUCOSIDASE Peptide, T12J13.8 Peptide, T12J13_8 Peptide, beta glucosidase 25 Peptide, PSPTO3318 Peptide, PSPTO4290 Peptide, GC Peptide, GCase Peptide, betaGC Peptide, glucosylceramidase beta Peptide, beta glucosidase 25 Peptide, beta-glucosidase Peptide, Beta-glucosidase Peptide, glucosidase, beta, acid Peptide, glucosylceramidase Peptide, bglX-2 Peptide, GBA Peptide, BGLU25 Peptide, PSPTO_3318 Peptide, bglX Peptide, bglA4 Peptide, Gba Peptide, LOC100399524 Peptide, bglA.2 Peptide, bglX-2 Peptide
    Background
    This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    59 kDa
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