Interleukin 3 Receptor, alpha (IL3RA) (C-Term) Peptide
Quick Overview for Interleukin 3 Receptor, alpha (IL3RA) (C-Term) Peptide (ABIN8103374)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- IL3RA Peptide - C-terminal region
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Sequence
- IQKRMQPVIT EQVRDRTSFQ LLNPGTYTVQ IRARERVYEF LSAWSTPQRF
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-IL3RA Antibody (ARP63751_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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Background
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Targeted Subunit: alpha
Background Information: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.
Alternative Symbols: CD123, IL3R, IL3RAY, IL3RX, IL3RY, MGC34174, hIL-3Ra
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Molecular Weight
- 41kDa
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Gene ID
- 3563
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NCBI Accession
- NP_002174
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UniProt
- P26951
Target
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