Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (N-Term) Peptide
Quick Overview for Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (N-Term) Peptide (ABIN8104084)
Target
Source
Application
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Protein Region
- N-Term
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Purpose
- CSEN Peptide - N-terminal region
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-CSEN antibody ( ARP31932_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
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Background
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Background Information: CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Alternative Symbols: CSEN, DREAM, KCHIP3
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Molecular Weight
- 29kDa
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Gene ID
- 30818
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NCBI Accession
- NP_038462
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UniProt
- Q9Y2W7
Target
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