Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (Middle Region) Peptide
Quick Overview for Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1) (Middle Region) Peptide (ABIN8104233)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- LRRFIP1 Peptide - middle region
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Sequence
- GPGSTDAQRT PPHAKERKKQ GKSEQQAEAL DSPQKKTKNK KKKNKKKKAA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- LRRFIP1 Antibody (ARP90467_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- LRRFIP1 (Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1))
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Background
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Background Information: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA (By similarity). Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity).
Alternative Symbols: Fliiap1, AU024550
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Molecular Weight
- 52 kDa
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Gene ID
- 16978
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NCBI Accession
- NP_001104781
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UniProt
- Q3UZ39
Target
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