Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) Peptide
LCK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN8104635
$145.08
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) Peptide (ABIN8104635)
Target
LCK
(Lymphocyte-Specific Protein tyrosine Kinase (LCK))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Purpose
- LCK Peptide - N-terminal region
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Sequence
- ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP LQDNLVIALH
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-LCK Antibody (ARP54524_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
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Background
- LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
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Molecular Weight
- 39kDa
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Gene ID
- 3932
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UniProt
- P06239
Target
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