Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) Peptide
Quick Overview for Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) Peptide (ABIN8105037)
Target
Source
Application
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Purpose
- ACADM Peptide
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Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) peptide
MCAD Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ACADM antibody ( ARP32788_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)
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Background
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Background Information: ACADM Is the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: ACAD1, MCAD, MCADH
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Molecular Weight
- 46kDa
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Gene ID
- 34
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NCBI Accession
- NP_000007
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UniProt
- P11310
Target
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