Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (Middle Region) Peptide
Quick Overview for Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (Middle Region) Peptide (ABIN8105039)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- ACADM Peptide - middle region
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Sequence
- FDACLITEEL AYGCTGVQTA IEANSLGQMP VILAGNDQQK KKYLGRMTEQ
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Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) peptide
MCAD Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- ACADM Antibody (ARP89968_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)
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Background
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Background Information: This gene encodes a homotetrameric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-double bond in a FAD-dependent reaction. As beta-oxidation cycles through its four steps, each member of the acyl-CoA dehydrogenase family works at an optimum fatty acid chain-length. This enzyme has its optimum length between C6- and C12-acylCoA. In mice, deficiency of this gene can cause neonatal mortality as well as fasting and cold intolerance. This gene has multiple, intronless pseudogenes.
Alternative Symbols: MCAD, AU018656
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Molecular Weight
- 46 kDa
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Gene ID
- 11364
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NCBI Accession
- NP_031408
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UniProt
- P45952
Target
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