Neurotensin Receptor 2 (NTSR2) (C-Term) Peptide
Quick Overview for Neurotensin Receptor 2 (NTSR2) (C-Term) Peptide (ABIN8106431)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- NTSR2 Peptide - C-terminal region
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Sequence
- AFLNGVTVSH LLALCSQVPS TSTPGSSTPS RLELLSEEGL LSFIVWKKTF
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Neurotensin Receptor 2 (NTSR2) peptide
NTSR2 Host: Synthetic BP, WB, IHC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-NTSR2 Antibody (ARP64147_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- NTSR2 (Neurotensin Receptor 2 (NTSR2))
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Background
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Background Information: The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
Alternative Symbols: NTR2
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Molecular Weight
- 45kDa
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Gene ID
- 23620
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NCBI Accession
- NP_036476
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UniProt
- O95665
Target
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