Neurotensin Receptor 2 (NTSR2) (C-Term) Peptide
NTSR2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981003
$160.46
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100 μg
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Quick Overview for Neurotensin Receptor 2 (NTSR2) (C-Term) Peptide (ABIN981003)
Target
NTSR2
(Neurotensin Receptor 2 (NTSR2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- AFLNGVTVSH LLALCSQVPS TSTPGSSTPS RLELLSEEGL LSFIVWKKTF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NTSR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Neurotensin Receptor 2 (NTSR2) peptide
NTSR2 Host: Synthetic BP, WB, IHC
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NTSR2 (Neurotensin Receptor 2 (NTSR2))
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Background
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The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
Alias Symbols: NTR2
Protein Interaction Partner: NTS
Protein Size: 410 -
Molecular Weight
- 45 kDa
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Gene ID
- 23620
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NCBI Accession
- NM_012344, NP_036476
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UniProt
- O95665
Target
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