NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) (N-Term) Peptide
Quick Overview for NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) (N-Term) Peptide (ABIN8106455)
Target
Source
Application
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Protein Region
- N-Term
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Purpose
- NKIRAS1 Peptide - N-terminal region
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-NKIRAS1 antibody ( ARP55370_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
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Background
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Background Information: NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Alternative Symbols: KBRAS1, kappaB-Ras1
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Molecular Weight
- 22kDa
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Gene ID
- 28512
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NCBI Accession
- NP_065078
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UniProt
- Q9NYS0
Target
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