NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) Peptide
NKIRAS1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all NKIRAS1 products
- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- CETMEDVYMA SVETDRGVKE QLHLYDTRGL QEGVELPKHY FSFADGFVLV
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of NKIRAS1 antibody,
Alternative Names: NKIRAS1 control peptide, NKIRAS1 antibody Blocking Peptide, Anti-NKIRAS1 Blocking Peptide, Nfkb Inhibitor Interacting Ras-Like 1 Blocking Peptide, KBRAS1 Blocking Peptide, kappaB-Ras1 Blocking Peptide, NKIRAS1, NKIRAS-1, NKIRAS 1, NKIRAS-1 Blocking Peptide, NKIRAS 1 Blocking Peptide - Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
- Synonyms
- NKIRAS1 Peptide, KBRAS1 Peptide, kappaB-Ras1 Peptide, zgc:92823 Peptide, kbras1 Peptide, 2400004O09Rik Peptide, NFKB inhibitor interacting Ras like 1 Peptide, NFKB inhibitor interacting Ras-like 1 Peptide, NFKB inhibitor interacting Ras-like 1 S homeolog Peptide, NFKB inhibitor interacting Ras-like protein 1 Peptide, NKIRAS1 Peptide, nkiras1 Peptide, nkiras1.S Peptide, Nkiras1 Peptide
- Background
- NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
- Molecular Weight
- 22 kDa
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