Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) Peptide
Quick Overview for Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) Peptide (ABIN8107811)
Target
Source
Application
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Purpose
- PPIA Peptide
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Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 143-155) peptide (Ovalbumin)
PPIA Reactivity: Human Host: Synthetic WB, Imm, SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-PPIA antibody ( ARP51352_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
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Background
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Background Information: PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Alternative Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397
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Molecular Weight
- 18kDa
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Gene ID
- 5478
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NCBI Accession
- NP_066953
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UniProt
- P62937
Target
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