Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) (Middle Region) Peptide
Quick Overview for Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) (Middle Region) Peptide (ABIN8109029)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- P4HA1 Peptide - middle region
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Sequence
- TKKLLELDPE HQRANGNLKY FEYIMAKEKD VNKSASDDQS DQKTTPKKKG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-P4HA1 Antibody (ARP62016_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
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Background
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Targeted Subunit: alpha-1
Background Information: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Alternative Symbols: P4HA
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Molecular Weight
- 59kDa
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Gene ID
- 5033
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NCBI Accession
- NP_000908
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UniProt
- P13674
Target
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