Protein Tob1 (TOB1) (Middle Region) Peptide
Quick Overview for Protein Tob1 (TOB1) (Middle Region) Peptide (ABIN8109492)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- TOB1 Peptide - middle region
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Sequence
- DLLKQKAISS SMHSLYGLGL GSQQQPQQQQ QPAQPPPPPP PPQQQQQQKT
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-TOB1 Antibody(ARP52105_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Protein Tob1 (TOB1)
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Background
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Background Information: This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Alternative Symbols: APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1
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Molecular Weight
- 38kDa
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Gene ID
- 10140
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NCBI Accession
- NP_005740
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UniProt
- P50616
Target
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