rho GTPase Activating Protein 26 (ARHGAP26) (Middle Region) Peptide
Quick Overview for rho GTPase Activating Protein 26 (ARHGAP26) (Middle Region) Peptide (ABIN8110496)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- ARHGAP26 Peptide - middle region
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Sequence
- LWMEAMDGRE PVYNSNKDSQ SEGTAQLDSI GFSIIRKCIH AVETRGINEQ
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-RHG26 Antibody (ARP73910_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
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Background
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Background Information: Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: GRAF, GRAF1, OPHN1L, OPHN1L1
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Molecular Weight
- 89kDa
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Gene ID
- 23092
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NCBI Accession
- NP_055886
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UniProt
- Q9UNA1
Target
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