Steroid Receptor RNA Activator 1 (SRA1) (N-Term) Peptide
Quick Overview for Steroid Receptor RNA Activator 1 (SRA1) (N-Term) Peptide (ABIN8112938)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- Sra1 Peptide - N-terminal region
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Sequence
- MMRCPAGGAE VEMAELYVKP GNKERGWNDP PQFSYGLQTQ TGGPKRTPLT
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-Sra1 Antibody(ARP37345_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
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Background
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Background Information: Sra1 is a functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Sra1 also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2).Sra1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. Sra1 may play a role in tumorigenesis.
Alternative Symbols: AA959952, SRA, STRAA1, Strra1, Sra, Srap, Straa1
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Molecular Weight
- 24kDa
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Gene ID
- 24068
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NCBI Accession
- NP_079567
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UniProt
- Q80VJ2
Target
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