Steroid Receptor RNA Activator 1 (SRA1) (N-Term) Peptide
SRA1
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all SRA1 products
- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MMRCPAGGAE VEMAELYVKP GNKERGWNDP PQFSYGLQTQ TGGPKRTPLT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Sra1 Antibody(ARP37345_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
- Synonyms
- SRA Peptide, SRAP Peptide, STRAA1 Peptide, pp7684 Peptide, AA959952 Peptide, Sra Peptide, Srap Peptide, Straa1 Peptide, Strra1 Peptide, zgc:86613 Peptide, steroid receptor RNA activator 1 Peptide, steroid receptor RNA activator 1 S homeolog Peptide, cytoplasmic FMR1 interacting protein 1 Peptide, SRA1 Peptide, Sra1 Peptide, sra1 Peptide, sra1.S Peptide, CYFIP1 Peptide
- Background
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Sra1 is a functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Sra1 also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2).Sra1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. Sra1 may play a role in tumorigenesis.
Alias Symbols: AA959952, SRA, STRAA1, Strra1, Sra, Srap, Straa1
Protein Interaction Partner: Pus1
Protein Size: 220 - Molecular Weight
- 24 kDa
- Gene ID
- 24068
- NCBI Accession
- NM_025291, NP_079567
- UniProt
- Q80VJ2
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