Translocation Protein 1 (TLOC1) (Middle Region) Peptide
Quick Overview for Translocation Protein 1 (TLOC1) (Middle Region) Peptide (ABIN8114340)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- SEC62 Peptide - middle region
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Sequence
- KYDKDIKKEK DKGKAESGKE EDKKSKKENI KDEKTKKEKE KKKDGEKEES
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-SEC62 Antibody (ARP64182_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))
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Background
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Background Information: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Alternative Symbols: Dtrp1, FLJ32803, HTP1, TLOC1, TP-1
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Molecular Weight
- 46kDa
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Gene ID
- 7095
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NCBI Accession
- NP_003253
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UniProt
- Q99442
Target
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