Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (Middle Region) Peptide
Quick Overview for Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (Middle Region) Peptide (ABIN8115239)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- USP7 Peptide - middle region
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Sequence
- QFFKSQGYRD GPGNPLRHNY EGTLRDLLQF FKPRQPKKLY YQQLKMKITD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- USP7 Antibody (ARP87494_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
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Background
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Background Information: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
Alternative Symbols: TEF1, HAUSP
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Molecular Weight
- 121 kDa
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Gene ID
- 7874
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NCBI Accession
- NP_001308787
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UniProt
- Q93009
Target
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