Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (Middle Region) Peptide
Quick Overview for Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (Middle Region) Peptide (ABIN8115249)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- UBE2V1 Peptide - middle region
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Sequence
- IYENRIYSLK IECGPKYPEA PPFVRFVTKI NMNGVNSSNG VVDPRAISVL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- UBE2V1 Antibody (ARP81840_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
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Background
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Background Information: Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alternative Symbols: CIR1, UEV1, CROC1, UBE2V, UEV-1, UEV1A, CROC-1
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Molecular Weight
- 24 kDa
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Gene ID
- 7335
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NCBI Accession
- NP_001027459
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UniProt
- Q13404
Target
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