Glucosamine (N-Acetyl)-6-Sulfatase (GNS) Peptide
Quick Overview for Glucosamine (N-Acetyl)-6-Sulfatase (GNS) Peptide (ABIN936100)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- YIFYTSDNGY HTGQFSLPID KRQLYEFDIK VPLLVRGPGI KPNQTSKMLV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Gns antibody,
Alternative Names: Gns control peptide, Gns antibody Blocking Peptide, Anti-Gns Blocking Peptide, glucosamine, N-acetyl-6-sulfatase Blocking Peptide, Gns Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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Background
- GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparin sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder ucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
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Molecular Weight
- 58 kDa
Target
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