Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (C-Term) Peptide
GNS
Reactivity: Rat
Host: Synthetic
BP, WB
Catalog No. ABIN977549
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (C-Term) Peptide (ABIN977549)
Target
GNS
(Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
Origin
Rat
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- YIFYTSDNGY HTGQFSLPID KRQLYEFDIK VPLLVRGPGI KPNQTSKMLV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Gns Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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Background
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GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparin sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder ucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
Alias Symbols: Gns
Protein Size: 519 -
Molecular Weight
- 58 kDa
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Gene ID
- 299825
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NCBI Accession
- NM_001011989, NP_001011989
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UniProt
- Q5M918
Target
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