G protein beta subunit-like (GBL) Peptide
GBL
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all GBL products
- GBL (G protein beta subunit-like (GBL))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- CAFSGDSQYI VTASSDNLAR LWCVETGEIK REYGGHQKAV VCLAFNDSVL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GBL antibody,
Alternative Names: GBL control peptide, GBL antibody Blocking Peptide, Anti-GBL Blocking Peptide, Glioblastoma Blocking Peptide, MGC111011 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- GBL (G protein beta subunit-like (GBL))
- Synonyms
- gbl Peptide, lts8 Peptide, GBL Peptide, GbetaL Peptide, LST8 Peptide, POP3 Peptide, WAT1 Peptide, 0610033N12Rik Peptide, AA409454 Peptide, AI505104 Peptide, AI851821 Peptide, Gbl Peptide, fi37e04 Peptide, wu:fi37e04 Peptide, zgc:55455 Peptide, zgc:85668 Peptide, MTOR associated protein, LST8 homolog L homeolog Peptide, MTOR associated protein, LST8 homolog Peptide, MTOR associated protein, LST8 homolog (S. cerevisiae) Peptide, mlst8.L Peptide, MLST8 Peptide, Mlst8 Peptide, mlst8 Peptide
- Background
- GBL is the subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin.
- Molecular Weight
- 36 kDa
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