Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) Peptide
MTHFD1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937137
Quick Overview for Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) Peptide (ABIN937137)
Target
MTHFD1
(Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- CMAKTHLSLS HNPEQKGVPT GFILPIRDIR ASVGAGFLYP LVGTMSTMPG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MTHFD1 antibody,
Alternative Names: MTHFD1 control peptide, MTHFD1 antibody Blocking Peptide, Anti-MTHFD1 Blocking Peptide, Methylenetetrahydrofolate Dehydrogenase Blocking Peptide, Nadp+ Dependent 1 Methenyltetrahydrofolate Cyclohydrolase Formyltetrahydrofolate Synthetase Blocking Peptide, MTHFC Blocking Peptide, MTHFD Blocking Peptide, MTHFD1, MTHFD-1, MTHFD 1, MTHFD-1 Blocking Peptide, MTHFD 1 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) peptide
MTHFD1 Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
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Background
- MTHFD1 possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
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Molecular Weight
- 101 kDa
Target
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