Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (Middle Region) Peptide
MTHFD1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MTHFD1 products
- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EWIKPGAIVI DCGINYVPDD KKPNGRKVVG DVAYDEAKER ASFITPVPGG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MTHFD1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) peptide
MTHFD1 Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
- Synonyms
- MTHFC Peptide, MTHFD Peptide, Tb07.27M11.970 Peptide, Dcs Peptide, E430024A07Rik Peptide, Mthfd Peptide, GB13160 Peptide, cb325 Peptide, fc29f07 Peptide, mthfd1 Peptide, wu:fc29f07 Peptide, zgc:55597 Peptide, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Peptide, C-1-tetrahydrofolate synthase, cytoplasmic Peptide, putative C-1-tetrahydrofolate synthase, cytoplasmic Peptide, putative C-1-tetrahydrofolate synthase,cytoplasmic Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b Peptide, c-1-tetrahydrofolate synthase, cytoplasmic Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase Peptide, MTHFD1 Peptide, Mthfd1 Peptide, Tc00.1047053509509.20 Peptide, Tc00.1047053511741.50 Peptide, Tc00.1047053511517.60 Peptide, Tc00.1047053508207.240 Peptide, Tb927.7.1600 Peptide, LINJ_26_0310 Peptide, LBRM_26_0350 Peptide, LMJF_26_0320 Peptide, mthfd1l Peptide, LOC550749 Peptide, mthfd1b Peptide, Tsp_00651 Peptide, mthfd1.L Peptide, mthfd1 Peptide, LOC589933 Peptide, LOC100634307 Peptide
- Background
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This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
Alias Symbols: MTHFC, MTHFD
Protein Size: 935 - Gene ID
- 4522
- NCBI Accession
- NM_005956, NP_005947
- UniProt
- P11586
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