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Poly(rC) Binding Protein 1 (PCBP1) Peptide

PCBP1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN937190
  • Target See all PCBP1 products
    PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    CSDAVGYPHA THDLEGPPLD AYSIQGQHTI SPLDLAKLNQ VARQQSHFAM
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of PCBP1 antibody,
    Alternative Names: PCBP1 control peptide, PCBP1 antibody Blocking Peptide, Anti-PCBP1 Blocking Peptide, Poly rC binding protein 1 Blocking Peptide, PCBP1, PCBP-1, PCBP 1, PCBP-1 Blocking Peptide, PCBP 1 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
    Synonyms
    PCBP1 Peptide, HNRPE1 Peptide, HNRPX Peptide, hnRNP-E1 Peptide, hnRNP-X Peptide, hnRNP E1 Peptide, WBP17 Peptide, [a]CP-1 Peptide, alphaCP-1 Peptide, RGD1561319 Peptide, poly(rC) binding protein 1 Peptide, poly(rC) binding protein 1 L homeolog Peptide, poly(rC)-binding protein 1 Peptide, PCBP1 Peptide, pcbp1.L Peptide, LOC100388387 Peptide, Pcbp1 Peptide
    Background
    PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.
    Molecular Weight
    39 kDa
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