Timeless Homolog (TIMELESS) Peptide
TIMELESS
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all TIMELESS products
- TIMELESS (Timeless Homolog (TIMELESS))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EEEDAVGKEP LKAAPKKRQL LDSDEEQEED EGRNRAPELG APGIQKKKRY
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TIMELESS antibody,
Alternative Names: TIMELESS control peptide, TIMELESS antibody Blocking Peptide, Anti-TIMELESS Blocking Peptide, timeless homolog, Drosophila Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- TIMELESS (Timeless Homolog (TIMELESS))
- Synonyms
- TIM Peptide, TIM1 Peptide, hTIM Peptide, C77407 Peptide, Debt69 Peptide, tim Peptide, CG3234 Peptide, Dmel\\CG3234 Peptide, Ritsu Peptide, Tim Peptide, dTIM Peptide, dTim Peptide, dtim Peptide, mel_tim Peptide, rit Peptide, tim1 Peptide, XTimeless1 Peptide, timeless Peptide, timelessb Peptide, TIMELESS Peptide, MXC20.14 Peptide, MXC20_14 Peptide, htim Peptide, im:6903167 Peptide, wu:fa95g04 Peptide, wu:fd23d07 Peptide, timeless circadian regulator Peptide, timeless circadian clock 1 Peptide, timeless Peptide, timeless circadian clock Peptide, timeless circadian clock S homeolog Peptide, timeless family protein Peptide, TIMELESS Peptide, Timeless Peptide, tim Peptide, timeless.S Peptide, Tim Peptide, ATIM Peptide, timeless Peptide, LOC100328917 Peptide
- Background
- The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
- Molecular Weight
- 139 kDa
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