Deoxynucleotidyltransferase, terminal (DNTT) Peptide
DNTT
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all TdT (DNTT) products
- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- FQDLVVFILE KKMGTTRRAF LMELARRKGF RVENELSDSV THIVAENNSG
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DNTT antibody,
Alternative Names: DNTT control peptide, DNTT antibody Blocking Peptide, Anti-DNTT Blocking Peptide, Deoxynucleotidyltransferase Terminal Blocking Peptide, TDT Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
- Synonyms
- TdT Peptide, TDT Peptide, BB160593 Peptide, Tdt Peptide, dntt-A Peptide, dntt Peptide, DNA nucleotidylexotransferase Peptide, deoxynucleotidyltransferase, terminal Peptide, DNA nucleotidylexotransferase L homeolog Peptide, terminal deoxynucleotidyl transferase Peptide, DNTT Peptide, dntt Peptide, Dntt Peptide, dntt.L Peptide, tdt Peptide
- Background
- DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor geneegments.
- Molecular Weight
- 58 kDa
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