Vacuolar-sorting Protein SNF8 (SNF8) Peptide
SNF8
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all SNF8 products
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- GTVLAEDQLA QMSKQLDMFK TNLEEFASKH KQEIRKNPEF RVQFQDMCAT
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Snf8 antibody,
Alternative Names: Snf8 control peptide, Snf8 antibody Blocking Peptide, Anti-Snf8 Blocking Peptide, SNF8, ESCRT-II complex subunit, homolog, S. cerevisiae Blocking Peptide, D11moh34 Blocking Peptide, MGC105799 Blocking Peptide, RGD1310144 Blocking Peptide, Snf8, Snf-8, Snf 8, Snf-8 Blocking Peptide, Snf 8 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- Synonyms
- d11moh34 Peptide, vps22 Peptide, Dot3 Peptide, EAP30 Peptide, VPS22 Peptide, D11moh34 Peptide, RGD1310144 Peptide, D11Moh34 Peptide, D11MOH34 Peptide, zgc:101578 Peptide, SNF8, ESCRT-II complex subunit Peptide, eap30 subunit of ell complex, putative Peptide, EAP30 subunit of ELL complex Peptide, SNF8, ESCRT-II complex subunit S homeolog Peptide, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) Peptide, snf8 Peptide, TA17290 Peptide, TVAG_107410 Peptide, Bm1_05145 Peptide, SNF8 Peptide, Snf8 Peptide, snf8.S Peptide
- Background
- Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
- Molecular Weight
- 28 kDa
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