Bone Morphogenetic Protein 10 (BMP10) Peptide
BMP10
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all BMP10 products
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Bmp10 antibody,
Alternative Names: Bmp10 control peptide, Bmp10 antibody Blocking Peptide, Anti-Bmp10 Blocking Peptide, bone morphogenetic protein 10 Blocking Peptide, Bmp10 Blocking Peptide, Bmp10, Bmp-10, Bmp 10, Bmp-10 Blocking Peptide, Bmp 10 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- Synonyms
- BMP10 Peptide, si:dkey-13n15.5 Peptide, Bmp10 Peptide, BMP9 Peptide, BMP-10 Peptide, bone morphogenetic protein 10 Peptide, BMP10 Peptide, bmp10 Peptide, LOC662386 Peptide, Bmp10 Peptide
- Background
- Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
- Molecular Weight
- 48 kDa
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