Bone Morphogenetic Protein 10 (BMP10) Peptide
BMP10
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939752
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 16 to 22 Business Days
Quick Overview for Bone Morphogenetic Protein 10 (BMP10) Peptide (ABIN939752)
Target
BMP10
(Bone Morphogenetic Protein 10 (BMP10))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Bmp10 antibody,
Alternative Names: Bmp10 control peptide, Bmp10 antibody Blocking Peptide, Anti-Bmp10 Blocking Peptide, bone morphogenetic protein 10 Blocking Peptide, Bmp10 Blocking Peptide, Bmp10, Bmp-10, Bmp 10, Bmp-10 Blocking Peptide, Bmp 10 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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Background
- Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
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Molecular Weight
- 48 kDa
Target
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