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Prohibitin 2 (PHB2) Peptide

PHB2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939919
  • Target See all Prohibitin 2 (PHB2) products
    Prohibitin 2 (PHB2)
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KLRKIRAAQN ISKTIATSQN RIYLTADNLV LNLQDESFTR GSDSLIKGKK
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of PHB2 antibody,
    Alternative Names: Prohibitin 2 control peptide, Prohibitin 2 antibody Blocking Peptide, Anti-Prohibitin 2 Blocking Peptide, BAP Blocking Peptide, BCAP37 Blocking Peptide, Bap37 Blocking Peptide, MGC117268 Blocking Peptide, PNAS-141 Blocking Peptide, REA Blocking Peptide, p22 Blocking Peptide, PHB2 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    Prohibitin 2 (PHB2)
    Synonyms
    bcap37 Peptide, zgc:73150 Peptide, wu:fc28c08 Peptide, PHB2 Peptide, phb2 Peptide, ATPHB2 Peptide, F21M11.21 Peptide, F21M11_21 Peptide, prohibitin 2 Peptide, DKFZp469N1310 Peptide, BAP Peptide, BCAP37 Peptide, Bap37 Peptide, PNAS-141 Peptide, REA Peptide, p22 Peptide, bap37 Peptide, prohibitin2 Peptide, xphb2 Peptide, AU044498 Peptide, Bcap37 Peptide, Bap Peptide, Bap-37 Peptide, Bcap27 Peptide, prohibitin 2a Peptide, prohibitin 2 Peptide, prohibitin 2 S homeolog Peptide, phb2a Peptide, PHB2 Peptide, phb2 Peptide, phb2.S Peptide, Phb2 Peptide
    Background
    PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
    Molecular Weight
    33 kDa
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