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Apolipoprotein E (APOE) Peptide

APOE Reactivity: Mammalian Host: Synthetic BP, IHC, WB
Catalog No. ABIN940102
  • Target See all APOE products
    APOE (Apolipoprotein E (APOE))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    KVLWAALLVT FLAGCQAKVE QAVETEPEPE LRQQTEWQSG QRWELALGRF
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of APOE antibody,
    Alternative Names: ApoE control peptide, ApoE antibody Blocking Peptide, Anti-ApoE Blocking Peptide, Apolipoprotein E Blocking Peptide, AD2 Blocking Peptide, MGC1571 Blocking Peptide, apoprotein Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    APOE (Apolipoprotein E (APOE))
    Synonyms
    ad2 Peptide, apoprotein Peptide, im:7036787 Peptide, wu:fb69a05 Peptide, zgc:110064 Peptide, apoe Peptide, AI255918 Peptide, AD2 Peptide, LDLCQ5 Peptide, LPG Peptide, APOEA Peptide, Apo-E Peptide, apolipoprotein E Peptide, apolipoprotein Ea Peptide, apoe Peptide, apoea Peptide, Apoe Peptide, APOE Peptide
    Background
    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
    Molecular Weight
    34 kDa
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