CD274 (PD-L1) (C-Term) Peptide
PD-L1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974662
Quick Overview for CD274 (PD-L1) (C-Term) Peptide (ABIN974662)
Target
PD-L1
(CD274 (PD-L1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- NVTSTLRINT TTNEIFYCTF RRLDPEENHT AELVIPELPL AHPPNERTHL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD274 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PD-L1 (CD274 (PD-L1))
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Background
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CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Alias Symbols: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1
Protein Interaction Partner: PDCD1,PDCD1
Protein Size: 290 -
Molecular Weight
- 32 kDa
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Gene ID
- 29126
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NCBI Accession
- NM_014143, NP_054862
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UniProt
- Q9NZQ7
Target
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