Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (N-Term) Peptide
Quick Overview for Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (N-Term) Peptide (ABIN976064)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- EPPPPRRLNM TTEQFTGDHT QHFLDGGEMK VEQLFQEFGN RKSNTIQSDG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DYRK3 Antibody(ARP30647_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))
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Background
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This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DYRK5, RED, REDK, hYAK3-2
Protein Size: 568 -
Molecular Weight
- 64 kDa
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Gene ID
- 8444
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NCBI Accession
- NM_001004023, NP_001004023
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UniProt
- D3DT79
Target
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