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Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (N-Term) Peptide

DYRK3 Reactivity: Human Host: Synthetic BP, WB, ICC
Catalog No. ABIN976065
$160.46
Plus shipping costs $50.00
100 μg
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Quick Overview for Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) (N-Term) Peptide (ABIN976065)

Target

DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
  • Protein Region

    N-Term

    Sequence

    GDHTQHFLDG GEMKVEQLFQ EFGNRKSNTI QSDGISDSEK CSPTVSQGKS

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-DYRK3 Antibody(ARP30648_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

    Background

    This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Alias Symbols: DYRK5, RED, REDK, hYAK3-2

    Protein Size: 588

    Molecular Weight

    66 kDa

    Gene ID

    8444

    NCBI Accession

    NM_003582, NP_003573

    UniProt

    O43781
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