H2A Histone Family, Member X (H2AFX) (N-Term) Peptide
H2AFX
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977821
$160.46
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100 μg
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Quick Overview for H2A Histone Family, Member X (H2AFX) (N-Term) Peptide (ABIN977821)
Target
H2AFX
(H2A Histone Family, Member X (H2AFX))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-H2AFX antibody (Catalog #: ARP58280_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- H2AFX (H2A Histone Family, Member X (H2AFX))
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Background
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H2AFX is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H2A.X, H2A/X, H2AX
Protein Interaction Partner: ATM,ALG9,ATM,BRCA1,H2AFX,MDC1,MRE11A,NBN,PPP1CA,SUPT5H,TP53BP1,WRN,ATR,BARD1,BLM,BRCA1,MDC1,NBN,PPM1D,RAD50,RAD51,TP53BP1,XPC
Protein Size: 143 -
Molecular Weight
- 16 kDa
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Gene ID
- 3014
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NCBI Accession
- NM_002105, NP_002096
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UniProt
- P16104
Target
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