H2A Histone Family, Member X (H2AFX) (Middle Region) Peptide
Quick Overview for H2A Histone Family, Member X (H2AFX) (Middle Region) Peptide (ABIN977822)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-H2AFX antibody (Catalog #: ARP58281_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- H2AFX (H2A Histone Family, Member X (H2AFX))
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Background
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA
Alias Symbols: H2A.X, H2A/X, H2AX
Protein Interaction Partner: ATM,ALG9,ATM,BRCA1,H2AFX,MDC1,MRE11A,NBN,PPP1CA,SUPT5H,TP53BP1,WRN,ATR,BARD1,BLM,BRCA1,MDC1,NBN,PPM1D,RAD50,RAD51,TP53BP1,XPC
Protein Size: 143 -
Molecular Weight
- 16 kDa
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Gene ID
- 3014
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NCBI Accession
- NM_002105, NP_002096
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UniProt
- P16104
Target
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